In terms of the longer acting stuff - Slin has no prefernce for which cells it uptakes to - fat or muscle - so how do you ensure you hit the muscle cells? I am assuming higher volume creates receptor sensitivity [muscle]?

There just seems to be so much confusion and bad info on Insulin when used in this field.

People actually use slow acting insulin? Chronically high insulin at supra-physiological levels would be a sure fire way to get diabetes.

RoB wrote:People actually use slow acting insulin? Chronically high insulin at supra-physiological levels would be a sure fire way to get diabetes.

erm yes. Alot use the slow acting.

In terms of your last comment - do you have anything to back that up? Only reason why I ask is that I used to think this and then had to change my stance as theres not any evidence to suggest that. Like testosterone - once you stop your bodies own comes back online.

hmm fair enough, never really looked into insulin use... i just assumed it was fast acting and used PWO only (As we all know assumption leads to the mother of all fuck ups) and from what i understand chronically high insulin will eventually lead to insulin resistance.

RoB wrote:hmm fair enough, never really looked into insulin use... i just assumed it was fast acting and used PWO only (As we all know assumption leads to the mother of all fuck ups) and from what i understand chronically high insulin will eventually lead to insulin resistance.

No nor have I - it was just something someone posted that got me thinking. How can you measure the fact that it will not uptake to fat cells as well? if its long acting

The pancreatic system isn't sensitive to negative feed back like the hpta is.
Also were not talking cronically high insulin levels. Long actng used for BB perposes is released over 15h (lantus/levimere). Lantus being better as it has a higher affinity for IGF-1 receptor sites.
As for insulin resistance I don't think its going to happen if you're of a good bf% and have an active lifestyle. Combine that with a healthy diet.. minimal risk.
I mean how many avid gym goers do you hear developing type II diabetes?

Insulin increases PS and nutrient uptake, the food you eat is what makes you fat. Clean food + long acting insulin is excellent.

http://www.ukiron.net has alot of studies and truly excellent info! Check it out.